Crosstalk between SLCs and Metabolism

©️ Authors

One of the aims in Re-Solute project is to profile the Metabolome of individual SLCs (Knockout- and Wildtype- OverExpression). A secondary goal is to map the functional relationships between SLCs based on integration of Metabolomics data with other high-throughput omics datasets.

Key Points

  • Six human cancer cell lines
  • Doxycycline (absent) as control
  • ~198 Metabolite Panel
  • 6470 Triple Quadrupole Mass Spectrometer
  • MassHunter 10.0 Software for initial Data Analysis
  • Machine Learning Model trained on initial manual peak-integrations
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Nara C. Marella
Senior Data Scientist & Data Manager

Biomedicine, Informatics, Life Sciences, Algorithms, Advanced Therapy Medicinal Products, Drug Discovery, Research Data Management, Laboratory Information Management Systems, Data Science, Team Management, Natural Sciences, IT Consulting, Statistics, Metabolomics, Proteomics, Transcriptomics, Machine Learning, Artificial Intelligence, Quality Control, Programming, Python, R, Volunteering, Graphic Design, Teaching, Problem Solving

Talks

Machine learning to automatize peak picking and peak integration
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